Physical activity, genetic and nutritional considerations in childhood weight management

References
1 Savage PJ, Bennett PH, Senter RG, Miller M: High prevalence of diabetes among young Pima
Indians. Diabetes 1979;28:937–942.
2 Dean H: NIDDM-Y in First Nation children in Canada. Clin Pediatr (Philadelphia) 1998;147:
52–57.
3 Pinhas-Hamiel O, Dolan LM, Daniels SR, Standiford D, Khoury PR, Zeitler P: Increased
incidence of non-insulin dependent diabetes mellitus among adolescents J Pediatr 1996;128:
608–615.
4 Scott CR, Smith JM, Cradock M, Pihoker C: Characteristics of youth – Onset non-insulindependent
diabetes mellitus and insulin-dependent diabetes mellitus at diagnosis. Pediatrics
1997;100:84–91.
5 Neufeld ND, Raffel LJ, Landon C, Chen Y-DI, Yadheim CM: Early presentation of type 2 diabetes
in Mexican-American youth. Diab Care 1998;21:80–86.
6 Hale DE, Danney KM: Non-insulin-dependent diabetes in Hispanic youth (type 2 Y). Diabetes
1998;47(suppl 1):A82.
7 Onyemere KU, Lipton RB: Parental history and early-onset type 2 diabetes in African-Americans
and Latinos in Chicago. J Pediatr 2002;141:825–829.
8 Grinstein G, Muzumdar R, Aponte L, Vuguin P, Saenger P, DiMartino-Nardi J: Presentation and
5-years follow-up of type 2 diabetes mellitus in African-American and Caribbean-Hispanic adolescents.
Horm Res 2002;60:121–126.
9 American Diabetes Association: Type 2 diabetes in children and adolescents. Diab Care 2000;23:
381–389.
10Rosenb loom AL, Joe JR, Young RS, Winter WE: Emerging epidemic of type 2 diabetes in youth.
Diab Care 1999;22:345–354.
11 Arslanian S: Type 2 diabetes in children clinical aspects and risk factors. Horm Res 2002;
57(suppl 1):19–28.
12 Libman I, Arslanian S: Type 2 diabetes in childhood: The American perspective. Horm Res 2003;
59(suppl 1):69–76.
13 Kiess W, Boettner A, Raile K, Kapellen T, Mueller G, Galler A, Paschke R, Wabitsch M: Type 2
diabetes mellitus in children and adolescents: A review from a European perspective. Horm Res
2003;59(suppl 1):77–84.
14 Fagot-Campagna A, Pettit DJ, Engelgaum MM, Burrows NR, Geiss LS, Valdez R, Beckles GLA,
Saaldine J, Gregg EW, Williams DF, Narayan KMV: Type 2 diabetes among North American children
and adolescents: An epidemiologic review and a public health persepective. J Pediatr 2000;
136:664–672.
15 King H, Rewers M: Diabetes in adults is now a third world problem. The WHO Ad Hoc Diabetes
Reporting Group. Bull WHO 1991;69:643–648.
16 Amos AF, McCarty DJ, Zimmet P: The rising global burden of diabetes and its complications:
Estimates and projections to the year 2010. Diab Med 1997;14:S1–S85.
17 Paulson EP, Richenderfer L, Ginsberg-Fellner F: Plasma glucose, free fatty acids and immunoreactive
insulin in sixty-six obese children. Diabetes 1986;17:261–269.
18 Jones KL: Non-insulin-dependent diabetes in children and adolescents: The therapeutic challenge.
Clin Pediatr (Philadelphia) 1998;37:103–110.
19 Jones KL, Haghi M: Type 2 diabetes mellitus on children and adolescence A primer. Endocrinologist
2000;10:389–396.
20 American Diabetes Association: Type 2 diabetes in children and adolescents. Diab Care 2000;23:
381–389.
21 Arslanian S: Type 2 diabetes mellitus in children: Pathophysiology and ‘risk factors’. J Pediatr
Endocrinol Metab 2000;13:1385–1394.
22 Kitagawa T, Owada M, Urakami T, Yamauchi K: Increased incidence of non-insulin dependent
diabetes among Japanese school children correlates with an increased intake of animal protein and
fat. Clin Pediatr 1998;37:111–115.
23 McGrath NM, Parker GN, Dawson P: Early presentation of type 2 diabetes mellitus in young
New Zealand Maori. Diab Res Clin Pract 1999;43:205–209.
Centers for Disease Control and Prevention: Prevalence of overweight among adolescents: United
States, 1998–91. MMWR 1994;43:818–821.
25 Troiano RP, Flegal KM, Kuczmarski RJ, Campbell SM, Johnson CL: Overweight prevalence and
trends for children and adolescents. The National Health and Nutrition Examination Surveys,
1963–91. Arch Pediatr Adolesc Med 1995;149:1085–1091.
26 Freedman DS, Srinivasan SR, Valdez RA, Williamson DF, Berenson GS: Secular increases in relative
weight and adiposity among children over two decades: The bogalusa Heart Study. Pediatrics
1997;99:420–426.
27 Orr DP: Contemporary management of adolescents with diabtes mellitus. 2. Type 2 diabetes.
Adolesc Hlth Update 2000;12:1–7.
28 Ludwig DS, Ebbelin CS: Type 2 diabetes mellitus in children. JAMA 2001;286:1427–1431.
29 Arslanian S: Type 2 diabetes in children: Clinical aspects and risk factors. Horm Res 2003;
57(suppl 1):19–28.
30Jones KL, Arslanian S, Peterokova VA, Park JS, Tomlinson MJ: Effect of metformin in pediatric
patients with type 2 diabetes: A randomized control trial. Diab Care 2002;25:89–94.
31 Libman IM, Pietropaolo M, Arslanian S, LaPorte RE, Becker DJ: Obese children with insulintreated
diabete: Is it type 1 or type 2? Presented at the 17th International Diabetes Federation
Congress, Mexico, Nov 2000. Diab Res Clin Pract 2000;50:5923.
32 Libman IM, Pietropaolo M, Arslanian SA, LaPorte RE, Becker DJ: Evidence for heterogeneous
pathogenesis of insulin-treated diabetes in black and white children. Diab Care 2000;26:
2876–2881.
33 Kobayashi K, Amemiya S, Higashida K, Ishihara T, Sawanobori E, Kobayashi K, Mochizuki M,
Kichuki N, Tokuyama K, Nakazawa S: Pathogenic factors of glucose intolerance in obese
Japanese adolescents with type 2 diabetes mellitus. Metabolism 2000;49:186–191.
34 Umpaichitra V, Bastian W, Taba D, Banereji MA, AvRuskin TW, Castells S: C-peptide and
glucagon profiles in minority children with type 2 diabetes mellitus. J Clin Endocrinol Metab
2001;86:1605–1609.
35 Willi SM, Kennedy A, Wojciechowski B, Garvey T: Insulin resistance and defective glucose
insulin coupling in ketosis-prone type 2 diabetes in African-Americans. Diabetes 1998;47:A306.
36 Arslanian S, Lewy VD, Danadian K: Glucose intolerance in obese adolescents with polycystic
ovary syndrome: Roles of insulin resistance and beta-cell dysfunction and risk of cardiovascular
disease. J Clin Endocrinol Metab 2001;86:66–71.
37 Dietz WH: Health consequences of obesity in youth: Childhood predictors of adult disease.
Pediatrics 1998;101:518–524.
38 Troiano RP, Flegal KM: Overweight children and adolescents: Description, epidemiology and
demographics. Pediatrics 1998;101:497–504.
39 Morton JF, Guthrie JF: Changes in children’s total fat intake and their food group sources of fat,
1998–91 versus 1994–95: Implications for diet quality. Fam Econ Nutr Rev 1998;11:44–57.
40Ludwig DS, Peterson KE, Gortmaker SL: Relation between consumption of sugar-sweetened
drinks and childhood obesity: A prospective observational analysis. Lancet 2001;357:505–508.
41 Svec F, Nastasi K, Hilton C, Bao W, Srinivasan SR, Berenson GS: Black-white contrasts in insulin
levels during pubertal development. The Bogalusa Heart Study. Diabetes 1992;41:313–317.
42 Gutin B, Islam S, Manos T, Cucuzzo N, Smith C, Stachura ME: Relation of percentage of body
fat and maximal aerobic capacity to risk factors for atherosclerosis and diabetes in black and white
seven to eleven-year-old children. J Pediatr 1994;125:647–652.
43 Arslanian S, Suprasongsin C: Insulin sensitivity, lipids, and body composition in childhood: Is
‘syndrome X’ present. J Clin Endocrinol Metab 1996;81:1058–1062.
44 Meigs JB, Avruch J: The metabolic syndrome. Endocrinol Rounds 2003;2:issue 5.
45 Alberti KG, Zimmer PZ: Definition, diagnosis and classification of diabetes mellitus and its complications.
1. Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation.
Diab Med 1998;15:539–553.
46 Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP)
Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult
Treatment Panel III). JAMA 2001;285:2486–2497.
The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Follow-up report
on the diagnosis and classification of diabetes mellitus. Diab Care 2003;26:3160–3167.
48 Steinberg HO, Baron AD: Vascular function, insulin resistance and fatty acids. Diabetologia
2002;45:623–634.
49 DeFronzo RA, Tobin JD, Andres R: Glucose clamp technique a method for quantifying insulin
secretion and resistance. Am J Physiol 1979;237:E214–E223.
50Hanson RL, Pratley RE, Bogardus C: Evaluation of simple indices of insulin sensitivity and
insulin secretion for use in epidemiological studies. Am J Epidemiol 2000;15:190–198.
51 Vuguin P, Saenger P, DiMartino-Nardi J: Fasting glucose insulin ratio: A useful measure of
insulin resistance in girls with premature adrenarche. J Clin Endocrinol Metab 2001;86:
4618–4621.
52 Ferranini E, Natali A, Bell P, Cavallo-Perin P, Lalic N, Mingrone G: Insulin resistance and hypersecretion
in obesity. European Group for the Study of Insulin Resistance (EGIR). J Clin Invest
1997;100:1166–1173.
53 Mauvais JF, Kulkarni RN, Kahn CR: Knockout models are useful tools to dissect the pathophysiology
and genetics of insulin resistance. Clin Endocrinol 2002;57:1–9.
54 DeFronzo RA: Pathogenesis of type 2 (non-insulin dependent) diabetes mellitus: A balanced
overview. Diabetologia 1992;35:389–387.
55 Bar-Or O, Foreyt J, Bouchard C: Physical activity, genetic and nutritional considerations in childhood
weight management. Med Sci Sports Exerc 1998;30:2–10.
56 Trent ME, Ludwig DS: Adolescent obesity, a need for greater awareness and improved, treatment.
Curr Opin Pediatr 1999;11:297–302.
57 Pi-Sunyer FX: A review of long-term studies evaluating the efficacy of weight loss in ameliorating
disorders associated with obesity. Clin Ther 1996;18:1006–1035.
58 Wing RR: Use of very-low-calorie diets in the treatment of obese persons with non-insulindependent
diabetes mellitus. J Am Diet Assoc 1995;95:569–572.
59 American Diabetes Association: Standards of medical care for patients with diabetes mellitus.
Diab Care 2000;23(suppl 1):s32–s41.
60DeF ronzo RA, Goodman AM: Efficacy of metformin in patients with non-insulin-dependent diabetes
mellitus. The Multicenter Metformin Study Group. N Engl J Med 1995;333:541–549.
61 Davidson MB, Peters AL: An overview of metformin in the treatment of type 2 diabetes mellitus.
Am J Med 1997;102:99–110.
62 Freemark MF, Bursey D: The effects of metformin on body mass index and glucose tolerance in
obese adolescents with fasting hyperinsuliemia and a family history of type 2 diabetes. Pediatrics
2001;107:E55.
63 Silverstein JH, Rosenbloom AL: Treatment of type 2 diabetes mellitus in children and adolescents.
J Pediatr Endocrinol Metab 2000;13:1403–1409.
64 Rosenbloom AL, Silverstein JH: Diabetes in the Child and Adolescent; in Lifshitz F (ed): Pediatric
Endocrinology, ed 4. New York, Dekker, 2003, pp 611–651.
65 Weiss R, Dufour S, Taksali SE, Tamborlane WV, Petersen KF, Bonadaonna RC, Boselli L,
Barbetta G, Allen K, Rife F, Savoye M, Dziura J, Sherwin R, Shulman GI, Saprio S: Prediabetes
in obese youth: A syndrome of impaired glucose tolerance, severe insulin resistance, and altered
myocellular and abdominal fat partitioning. Lancet 2003;362:951–957.
66 Singhal A, Fewtrell M, Cole TJ, Lucas A: Low nutrient intake and early growth for later insulin
resistance in adolescents born preterm. Lancet 2003;361:1089–1097.
67 Rosenbloom AL: Obesity, insulin resistance, B-cell autoimmunity, and the changing clinical
epidemiology of childhood diabetes. Diab Care 2003;26:2954–2955.